Lifestyle

High protein, low carb diet will shorten your lifespan

A DIET high in protein and low in carbohydrates could lead to a shorter lifespan, a ground-breaking study has found.

Conducted by the University of Sydney's Charles Perkins Centre, the world-first research examines the effects of protein, fat and carbohydrate on energy intake, metabolic health, ageing and longevity in mice.

The research demonstrated in mice that calorie restriction, achieved by high protein diets or dietary dilution, has no beneficial effects on lifespan, a phenomenon researchers predict will apply in humans.

While a high protein, low carbohydrate diet resulted in reduced body fat and food intake, it also led to a shorter lifespan and poor cardiometabolic health.

By contrast, a high carbohydrate, low protein diet resulted in longer lifespan and better cardiometabolic health, despite also increasing body fat.

A low protein, high fat diet provided the worst health outcomes, with fat content showing no negative influence on food intake.

"This research has enormous implications for how much food we eat, our body fat, our heart and metabolic health, and ultimately the duration of our lives," said Professor Steve Simpson, Academic Director of the Charles Perkins Centre and corresponding author of the study.

"We have shown explicitly why it is that calories aren't all the same - we need to look at where the calories come from and how they interact."

"This represents an enormous leap in our understanding of the impact of diet quality and diet balance on food intake, health, ageing and longevity," said co-author Professor David Le Couteur, from the University's Charles Perkins Centre and Professor of Geriatric Medicine at Concord Hospital.

"We now face a new frontier in nutrition research."

By examining mice fed a variety of 25 diets, the research team used an innovative state-space nutritional modelling method to measure the interactive effects of dietary energy, protein, fat and carbohydrate on food intake, cardiometabolic health and longevity.

The results suggest that lifespan could be extended in animals by manipulating the ratio of macronutrients in their diet - the first evidence that pharmacology could be used to extend lifespan in normal mammals.

Although mice were the subjects of this study, Professor Le Couteur said the results from the study accord with previous research in humans, but with a much larger number of dietary treatments and nutritional variables.

"Up until this point, most research has either concentrated on a single nutritional variable, such as fat, carbohydrate or calories, so much of our understanding of energy intake and diet balance is based on one-dimensional single nutrient assessments," he said.

"The advice we are always given is to eat a healthy balanced diet, but what does that mean? We have some idea, but in relation to nutritional composition we don't know terribly well. This research represents an important step in finding out."

Researchers predict that a diet with moderate amounts of high quality protein (around 15 to 20 percent of total calorie intake), that is relatively low in fat and high in good quality complex carbohydrates will yield the best metabolic health and the longest life.

Professor Simpson is Academic Director of the Charles Perkins Centre, a world-leading initiative that brings together international leaders across a broad spectrum of academic disciplines to find real-world solutions to obesity, diabetes and cardiovascular disease.

The state-of-the-art Charles Perkins Centre building, a $385 million teaching and research hub on the University of Sydney's Camperdown Campus, will officially launch later this year.

Topics:  diet editors picks fat mice



10 best street art spots to take an Insta selfie

IF YOU are in need of a few trendy new Instagram snaps, then get your phone and selfie-stick ready and head to Brisbane.

Theatre royalty graces Brisbane stage

Don't miss Charles Edwards in this incredible theatre performance.

WHEN acting royalty comes to town, you sit up and take notice.

Don’t go chasing waterfalls…find them on these drives!

The Scenic Rim is just one place nearby that you'll love.

BRISBANE isn’t all bright lights and city slickers.

Your boots are made for walking these tours

Brisbane Greeters tours are a great way to learn the local history of the city.

YOU don’t need a bike or bus for a seriously good tour of Brisbane.

Drink where the cool kids do this summer

There are a bunch of new bars open in Brisbane, make sure you're there!

CHECK out these new funky bars.

Discover Brisbane’s laneway gems

Brisbane's laneways will surprise you.

NOT all of Brisbane City is as it seems…

Science Festival seriously awesome

Don't miss the World Science Festival Brisbane!

CALLING everyone who wants to see something totally cool.

150 residents meet to fight for their dump

FIGHT BACK: Residents met with council representatives over fears the Avondale Waste Facility would close.

Councillor promises to fight tooth and nail

Bundy's little brave heart after third operation

BRAVE HEART: Bundaberg's little Noah Lammi has undergone his third open heart surgery. He is now recovering in Lady Cilento Hospital Brisbane.

Another open heart surgery for Bundaberg youngster

WATCH: Fire close to homes, firefighters work to control it

Emergency crews work to control Burnett Heads fire

Residents are urged to keep there windows shut as smoke fills air

Local Partners

Theatre royalty graces Brisbane stage

WHEN acting royalty comes to town to direct the theatre performance of the year, you sit up and take notice.

Un-American tale makes Lion weakest link in Oscars line-up

Dev Patel in a scene from the movie Lion.

PSYCHOLOGY researchers find US films most likely to win at Oscars.

Can rightful winner Midnight take out golden Gosling in Oscars?

Can Lion pip La La Land at the post in this year's Oscars? Sunny Pawar (pictured) helped bring a powerful film to the big screen.

WILL Aussie film Lion triumph or will popular La La Land prevail?

Living End, Grinspoon stars hit stage for American Idiot

Chris Cheney of The Living End stars in the Australian production of Green Days musical American Idiot at Brisbane's QPAC Theatre.

TAKE a look behind the scenes of Green Day's American Idiot musical

Samuel L Jackson dismisses La La Land ahead of Oscars

Ryan Gosling and Emma Stone in a scene from the movie La La Land.

Hollywood actor and Oscars voter says Denzel should win top gong

'Why we drove 800km to buy a treehouse with a disco ball'

The new owners have planned a few updates, but will stick with much of the original design.

A couple travelled almost 800km for the home of their dreams.

The trick homeowners are using to buy more properties

Chantelle Subritzky leaves her home each week for Airbnb guests.

Queenslanders are going down this path to help pay their mortgages

Stunning home blends South Pacific beauty with Orient style

Immaculate residence with two outdoor living areas

$140k damage: landlord says property trashed, contaminated

He had what he calls "the tenants from hell"

Submarine, buses and 3000 tyres removed in $100K clean up

The list of things removed from this property is beyond astonishing

Ready to SELL your property?

Post Your Ad Here!