Lifestyle

High protein, low carb diet will shorten your lifespan

A DIET high in protein and low in carbohydrates could lead to a shorter lifespan, a ground-breaking study has found.

Conducted by the University of Sydney's Charles Perkins Centre, the world-first research examines the effects of protein, fat and carbohydrate on energy intake, metabolic health, ageing and longevity in mice.

The research demonstrated in mice that calorie restriction, achieved by high protein diets or dietary dilution, has no beneficial effects on lifespan, a phenomenon researchers predict will apply in humans.

While a high protein, low carbohydrate diet resulted in reduced body fat and food intake, it also led to a shorter lifespan and poor cardiometabolic health.

By contrast, a high carbohydrate, low protein diet resulted in longer lifespan and better cardiometabolic health, despite also increasing body fat.

A low protein, high fat diet provided the worst health outcomes, with fat content showing no negative influence on food intake.

"This research has enormous implications for how much food we eat, our body fat, our heart and metabolic health, and ultimately the duration of our lives," said Professor Steve Simpson, Academic Director of the Charles Perkins Centre and corresponding author of the study.

"We have shown explicitly why it is that calories aren't all the same - we need to look at where the calories come from and how they interact."

"This represents an enormous leap in our understanding of the impact of diet quality and diet balance on food intake, health, ageing and longevity," said co-author Professor David Le Couteur, from the University's Charles Perkins Centre and Professor of Geriatric Medicine at Concord Hospital.

"We now face a new frontier in nutrition research."

By examining mice fed a variety of 25 diets, the research team used an innovative state-space nutritional modelling method to measure the interactive effects of dietary energy, protein, fat and carbohydrate on food intake, cardiometabolic health and longevity.

The results suggest that lifespan could be extended in animals by manipulating the ratio of macronutrients in their diet - the first evidence that pharmacology could be used to extend lifespan in normal mammals.

Although mice were the subjects of this study, Professor Le Couteur said the results from the study accord with previous research in humans, but with a much larger number of dietary treatments and nutritional variables.

"Up until this point, most research has either concentrated on a single nutritional variable, such as fat, carbohydrate or calories, so much of our understanding of energy intake and diet balance is based on one-dimensional single nutrient assessments," he said.

"The advice we are always given is to eat a healthy balanced diet, but what does that mean? We have some idea, but in relation to nutritional composition we don't know terribly well. This research represents an important step in finding out."

Researchers predict that a diet with moderate amounts of high quality protein (around 15 to 20 percent of total calorie intake), that is relatively low in fat and high in good quality complex carbohydrates will yield the best metabolic health and the longest life.

Professor Simpson is Academic Director of the Charles Perkins Centre, a world-leading initiative that brings together international leaders across a broad spectrum of academic disciplines to find real-world solutions to obesity, diabetes and cardiovascular disease.

The state-of-the-art Charles Perkins Centre building, a $385 million teaching and research hub on the University of Sydney's Camperdown Campus, will officially launch later this year.

Topics:  diet, editors picks, fat, mice




Bundaberg could feed the state with the food we throw out

Just how much food do we waste every year?

No jail for league player who punched man

ASSAULT: The impact of the punch broke the victim's left front tooth and caused a puncture wound to his lip.

Nine-month community correction order for CBD assault

Jail drug smuggler caught with five bags of pot

BACK IN COURT: Brooke Marie Glasson was found in possession of marijuana two months after pleading guilty to supplying a dangerous drug at the Maryborough Correctional Centre.

Second chance to stay out of jail

Latest deals and offers

The Hard Word reviews Kyzer Soze

Kyzer Soze are playing Brisbane tomorrow at the Crowbar in Fortitude Valley. Photo Contributed

Kyzer Soze summon the evil for this mighty slab of death metal

Britney Spears 'almost drowned' in Hawaii

Britney Spears has revealed she 'almost drowned' while on holiday

Doco reveals real story behind Black Hawk Down

Former Black Hawk pilot Mike Durant shares his story, which helped to inspire the movie Black Hawk Down, in the TV series No Man Left Behind.

FORMER pilot recounts ordeal which inspired a Hollywood movie.

What's on the big screen this week

Toby Kebbell and Jack Huston in a scene from the movie Ben-Hur.

AN OLD classic returns to the big screen with a new young star.

Bachelor Richie gives bacon-loving Noni the boot

Noni Janur features on this season of The Bachelor.

TOOWOOMBA swimwear designer still single but focusing on her career.

Zumbo's Just Desserts serves up magical dishes

Gigi Falanga, left, joins hosts Adriano Zumbo and Rachel Khoo on the TV series Zumbo's Just Desserts.

ADRIANO Zumbo’s decadent creations have become prime-time viewing.

ISLAND FOR SALE: Cheap Fraser Coast island drops price again

Suna Island in the Great Sandy Strait will be auctioned by Ray White Hervey Bay on Saturday morning.

This is the cheapest island you will find for sale in Australia

How a family home can fit on a 250sq m block

This is what you can build on 250m2.

Here's the floor plan of a home built on 250sq m

$100m plan for Curtis Island 'world class' luxury resort

$100 million resort: Top views at Turtle Street at Curtis Island.

"At the moment we think it meets all the town planning approvals.”

Coast building approvals at seven-year high: report

The the 2015/16 Development Indicators Annual Highlights Report documents local development activity that took place during the last financial year.

New report shows increasing development on the Sunshine Coast

Top honours for Mackay and Whitsunday builders

The Kerrisdale Gardens property from Paynter Dixon Queensland which won them Project of the Year.

Mackay and Whitsunday builders awarded top honours last night.

Investors eye Gladstone's $4m island with resort approval

UP FOR SALE: Turtle Island is on the market.

CHINESE and Sydney investors flag interest in Gladstone island.